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CompoundIQ publishes research summaries for informational and educational purposes only. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. Always consult a licensed healthcare provider. Many compounds listed are research chemicals not approved for human use.

SteroidAdvancedVery High Risk

Tetrahydrogestrinone

Also known as: THG, The Clear

Tetrahydrogestrinone (THG), known as 'The Clear,' is the infamous designer steroid at the center of the BALCO scandal. It was created by chemist Patrick Arnold specifically to be undetectable in anti-doping tests. It is a modified form of gestrinone and trenbolone, combining potent anabolic effects with stealth properties.

Evidence25/100 — Emerging

Risk Level

Very High Risk

Difficulty

Advanced
CAS Number5949-44-0
Molecular FormulaC21H28O2
ClassSteroid
CategoryUnderground Steroids

Mechanism of Action

A potent androgen and progestogen derived from gestrinone. Binds strongly to both androgen and progesterone receptors. Has glucocorticoid antagonist properties. Does not aromatize to estrogen. Its structure is similar to trenbolone but with additional modifications that originally prevented detection in standard drug tests.

Dosing Research

No clinically established dosing. Was reportedly administered sublingually in microgram quantities due to extreme potency. Exact dosing protocols used by BALCO athletes remain largely undisclosed. Now classified as a Schedule III controlled substance in the US.

Side Effects & Risks

Expected to share the severe side effect profile of trenbolone including cardiovascular toxicity, HPTA suppression, and progestogenic effects. Liver toxicity risk. No human clinical safety data exists. The compound was never subjected to any formal safety evaluation before being used by athletes.

Research Studies

Disclaimer

CompoundIQ publishes research summaries for informational and educational purposes only. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. Always consult a licensed healthcare provider. Many compounds listed are research chemicals not approved for human use.

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