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CompoundIQ publishes research summaries for informational and educational purposes only. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. Always consult a licensed healthcare provider. Many compounds listed are research chemicals not approved for human use.

OtherIntermediateLow Risk

Meldonium

Also known as: Mildronate

Meldonium is a cardioprotective drug developed in Latvia, widely used in Eastern Europe for heart conditions. It gained international attention after being banned by WADA in 2016, with many athletes testing positive.

Evidence58/100 — Moderate

Risk Level

Low Risk

Difficulty

Intermediate
CAS Number76144-81-5
Molecular FormulaC6H14N2O2
ClassOther
CategoryOther Performance Compounds

Mechanism of Action

Meldonium inhibits carnitine biosynthesis by blocking gamma-butyrobetaine hydroxylase. This shifts cellular energy metabolism from fatty acid oxidation to glucose oxidation, which is more oxygen-efficient. It also increases nitric oxide production and reduces carnitine-mediated transport of long-chain fatty acids into mitochondria.

Dosing Research

Therapeutic dose: 500-1000 mg/day orally or IV. Typically used in 4-6 week cycles with breaks. Half-life approximately 4-6 hours. Available as capsules or injection in Eastern Europe.

Side Effects & Risks

Generally well-tolerated at therapeutic doses. Possible GI discomfort, allergic reactions. Banned by WADA since 2016. Limited Western safety data. Long-term effects of chronic use not well studied.

Research Studies

Disclaimer

CompoundIQ publishes research summaries for informational and educational purposes only. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. Always consult a licensed healthcare provider. Many compounds listed are research chemicals not approved for human use.

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